Effects of Photobiomodulation With Two Wavelengths on Diabetic Peripheral Neuropathy

This clinical study evaluated the effects of Photobiomodulation Therapy (PBMT) using two wavelengths (660 nm and 850 nm) on patients with Diabetic Peripheral Neuropathy (DPN)—a common complication of diabetes that affects nerve function, sensation, and circulation. The goal was to assess whether PBMT could improve symptoms and functional outcomes.

Key Findings

  • PBMT significantly improved neuropathic pain, sensation, and nerve-related symptoms in patients with DPN.
  • Treatment also helped improve balance and functional mobility, which may reduce fall risk and improve quality of life.
  • Using dual wavelengths (red and near-infrared light) may enhance tissue penetration and therapeutic response.
  • PBMT showed promise as a non-invasive supportive therapy for nerve recovery and symptom management.

Clinical Importance

This study suggests PBMT may be useful as an adjunct treatment for diabetic peripheral neuropathy, potentially helping reduce pain and improve nerve function without replacing standard diabetic care.

Limitations

  • Sample size was limited.
  • Focused on a specific patient group with DPN.
  • More large-scale clinical trials are needed to confirm long-term benefits and ideal treatment protocols.

Conclusion

Photobiomodulation with 660 nm and 850 nm wavelengths showed promising benefits for improving pain, sensory function, and mobility in diabetic peripheral neuropathy patients, supporting its role as a potential complementary therapy in diabetes-related nerve care.

Simple takeaway: PBMT may help relieve nerve pain and improve function in people with diabetic neuropathy, especially when using red and near-infrared light. 

https://pmc.ncbi.nlm.nih.gov/articles/PMC10423950/

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