Mechanisms and Applications of the Anti-Inflammatory Effects of Photobiomodulation (2017)
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This review explains how photobiomodulation (PBM), also known as low-level laser or red/near-infrared light therapy, helps reduce inflammation and supports healing. PBM works by delivering light to tissues, which affects cellular activity—especially mitochondria—leading to increased energy (ATP production), reduced oxidative stress, and modulation of inflammatory signaling pathways.
The study highlights that PBM can reduce both acute and chronic inflammation by influencing immune cells, cytokines, and blood flow. It may also decrease swelling, pain, and tissue damage while promoting repair.
The paper also discusses potential clinical uses of PBM for conditions such as wound healing, arthritis, muscle injuries, lung inflammation, neurological disorders, and chronic pain. However, the authors note that treatment effectiveness depends on factors like wavelength, dose, timing, and treatment location.
Key takeaway: PBM shows strong potential as a non-invasive therapy to reduce inflammation and improve healing, but proper treatment parameters are critical for best results.
Excerpt (short): PBM has “pronounced anti-inflammatory effects” through both local and systemic mechanisms.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5523874/