Photobiomodulation Therapy in Diabetes-Related Complications and Tissue Regeneration
Share
This review explores the therapeutic role of photobiomodulation therapy (PBMT) in managing diabetes-related complications, tissue repair, and regenerative healing. PBMT uses low-intensity red or near-infrared light to stimulate biological activity that supports healing, reduces inflammation, and improves cellular function without causing tissue damage.
The article explains that PBMT primarily acts through mitochondrial stimulation, particularly cytochrome c oxidase, which increases ATP production, regulates reactive oxygen species (ROS), improves microcirculation, and activates signaling pathways involved in cell proliferation, angiogenesis, collagen formation, and tissue regeneration. These effects may improve wound healing and reduce oxidative stress often associated with chronic diabetic conditions.
The review highlights PBMT’s potential applications in diabetic wounds, peripheral neuropathy, vascular dysfunction, chronic inflammation, and impaired tissue repair. It also emphasizes that treatment success depends on factors such as wavelength, dosage, treatment duration, and exposure depth.
Key takeaway: PBMT appears to be a promising non-invasive supportive therapy for diabetes-related tissue damage and regenerative healing, but further standardized clinical studies are needed to confirm effectiveness and optimize treatment protocols.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11993076/